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本文综述了1985年以来部分英文文献中有关心钠素(ANP)在儿科临床的研究进展,着重分析了围产期新生儿及早产儿ANP增高;先心病房缺及室缺ANP水平取决于QP/QS的大小,充血性心衰多由容量扩张。及陈发性室上性心动过速时的心房壁紧张均可刺激ANP释放;ANP能增加肾小滤球过率,对有容量扩张的晚期肾衰的治疗优于常用利尿剂;高血压时ANP水平报告不一。此外还分析了其他疾病时的ANP水平,提示ANP参与许多疾病的发生,并可用于临床治疗。
This review summarizes the progress of pediatric clinical trials of atrial natriuretic peptide (ANP) in some English articles since 1985, and focuses on the analysis of increased ANP in perinatal neonates and premature infants. The levels of ANP in the absence of ventricular and ventricular aneurysm depend on the QP / The size of QS, congestive heart failure and more by the capacity expansion. And atrial tachycardia in the anamnesis of supraventricular tachycardia can stimulate ANP release; ANP can increase the rate of renal small filtration rate of the capacity of the treatment of advanced renal failure is better than the commonly used diuretics; hypertension Different levels of ANP report. In addition, ANP levels in other diseases were also analyzed, suggesting that ANP is involved in many diseases and can be used for clinical treatment.