论文部分内容阅读
目的:探讨中晚期食管癌同期放化疗疗效及毒性反应。方法:随机分单放组(A)、放化组(B)各48例。第1~4天DF方案化疗;常规放疗。结果:B组1、3 a生存率高于A组(P<0.01),5 a生存率无统计学意义(P>0.05)。B组毒性反应增加,有统计学意义(P<0.01)。结论:以DF方案化疗同期放疗中晚期食管癌,近期疗效较好,有提高远期生存率可能,虽毒性反应增加但能耐受。
Objective: To investigate the efficacy and toxicity of concurrent chemoradiotherapy in advanced esophageal cancer. Methods: Randomly divided group (A), radiotherapy group (B) 48 cases. Day 1 to 4 days DF regimen chemotherapy; conventional radiotherapy. Results: The 1,3 and 3-year survival rates in group B were significantly higher than those in group A (P <0.01). There was no significant difference in 5-year survival rates (P> 0.05). The toxicity of group B increased, with statistical significance (P <0.01). Conclusion: The concurrent chemotherapy with DF regimen in the treatment of advanced esophageal cancer, the recent curative effect is better, improve the long-term survival rate may be, although the increased toxicity but can tolerate.