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【目的】 研究健康学龄儿童幽门螺杆菌 (helicobactorpylori ,Hp)感染状况。 【方法】 采用13 C尿素呼吸试验 (13 C ureabeathtest:13 C UBT)及血清ELISA法检测抗Hp IgG。 【结果】 14 2例儿童中 (男 5 7例、女 85例 )。13 C UBT及Hp IgG的阳性率分别为 12 .7% ,40 .9% ;其中 9～ 10岁 82例中13 C UBT及Hp IgG的阳性率分别为 10 .98%和3 7.81% ;12～ 13岁 60例中13 C UBT及Hp IgG的阳性率分别为 15 %和 5 0 %。两个年龄组间13 C UBT及Hp IgG的Hp感染率无统计学差异 ,性别也无差异 (P >0 .0 5 )。 【结论】 ①健康儿童Hp无症状感染状况不容忽视 ;②13 C UBT检测健康儿童Hp感染状况方法简单、安全、快速且准确性高 ,为检测Hp无症状感染的有效手段 ,也适用于Hp感染的流行病学调查
【Objective】 To investigate the infection of helicobacter pylori (Hp) in healthy school-age children. 【Method】 Anti-Hp IgG was detected by 13 C urea test (13 C UBT) and serum ELISA. 【Results】 There were 14 2 children (57 males and 85 females). The positive rates of 13 C UBT and Hp IgG were 12.7% and 40.9%, respectively. The positive rates of 13 C UBT and Hp IgG in 82 cases aged 9-10 years were 10.98% and 3 7.81%, respectively. 12 The positive rates of 13 C UBT and Hp IgG in ~ 13 years old were 15% and 50% respectively. Hp infection rates of 13 C UBT and Hp IgG between the two age groups were not statistically different, no difference in sex (P> 0.05). 【Conclusion】 ① The status of Hp asymptomatic infection in healthy children can not be ignored. ② The detection of Hp infection by healthy children with13C UBT is simple, safe, rapid and accurate. It is an effective measure to detect Hp asymptomatic infection and also suitable for Hp infection Epidemiological Investigation