【目的】观察东菱精纯克栓酶 (DF 5 2 1)对频发性短暂性脑缺血发作 (TIA)的疗效。【方法】 5 0例TIA患者随机分为DF 5 2 1观察组 ( 2 8例 )和常规治疗对照组 ( 2 2例 )。【结果】观察组治疗后 2 4h及 3天内TIA发作控制率为 75 %和 10 0 % ,均明显高于对照组 36 3 %和77 2 % ,随访一年观察组 4例再次TIA发作 ,2例发生脑梗死 ,分别为 14 2 %和 7 1% ,对照组有 9例TIA发作 ,6例发生脑梗死 ,分别为 40 %和 2 7 2 %。【结论】DF 5 2 1治疗TIAs疗效是显著的 ,且起效快 ,复发率低 ,安全性高 ,远期效果好。 【Objective】 To observe the curative effect of DF Ling (2115) on patients with frequent transient ischemic attack (TIA). 【Methods】 Fifty TIA patients were randomly divided into DF 5 2 1 observation group (28 cases) and routine treatment control group (22 cases). 【Results】 The control rates of TIA in observation group within 24 h and 3 days after treatment were 75% and 100%, respectively, which were significantly higher than 36 3% and 77 2% in control group. In the one year follow-up observation group, 4 cases had TIA again and 2 The incidence of cerebral infarction was 14 2% and 71% respectively. In the control group, 9 patients had TIA episode and 6 patients had cerebral infarction, 40% and 272% respectively. 【Conclusion】 The efficacy of DF 5 2 1 in the treatment of TIAs is significant, with rapid onset, low recurrence rate, high safety and long-term efficacy.