原发性骨髓纤维化(简称骨纤)转化为急性粒细胞型白血病(简称急粒)少见报道,现将我院收治的一例总结。男,17岁,农民,住院号67442。患者于1981年1月起经常觉上腹部隐痛,乏力,面色苍白,逐渐衰弱。同年7月初因受凉后头痛,鼻塞,高热,于1981年7月29日入院。家族史无特殊。体查:体温37.8℃,呼吸18次,脉搏100次,血压100/80。神清,慢性病容,面色苍白。皮肤无出血点,全身浅表淋巴结无肿大。心尖区有Ⅱ级收缩期杂音。肝肋下2cm,脾肋下2~+cm。实验室检查:肝功能正常。血培养两次阴性。血红蛋白7.5～3.4g,红细胞206～120万。白细胞4450～200/mm~3,原粒2.3％,原+早35～60％。过 Primary myelofibrosis (referred to as bone fiber) into acute myeloid leukemia (referred to as acute particles) rare reports, now a summary of our hospital admitted. Male, 17 years old, farmer, hospital number 67442. Patients in January 1981 often feel upper abdominal pain, fatigue, pale, gradually weakened. The same year in early July due to cold headache, stuffy nose, high fever, on July 29, 1981 admission. No special family history. Physical examination: body temperature 37.8 ℃, breathing 18 times, pulse 100 times, blood pressure 100/80. Clear, chronic disease, pale. No bleeding skin, systemic superficial lymph nodes without swelling. Apex Ⅱ grade systolic murmur. Liver ribs 2cm, Spleen ribs 2 ~ + cm. Laboratory tests: normal liver function. Blood culture twice negative. Hemoglobin 7.5 ~ 3.4g, red blood cells 206 ~ 1.2 million. White blood cells 4450 ~ 200 / mm ~ 3, 2.3% of the original particles, the original + 35 ~ 60% early. Too