患者:女,43a。因患风湿性关节炎,以往经常服肠溶阿斯匹林片,于1991年11月20日早饭后服吲哚拉新胶囊300mg(沈阳第五制药厂,批号910603),午饭后约10min 又服300mg,感觉上半身稍有紧皱,1h 后该症状有所加重,未引起注意。晚饭后,再次服用吲哚拉新300mg,约0.5h 后,全身皮肤开始阵阵发紧、出汗,四肢肌肉酸困不适。继之出现全身皮肤感觉过敏,触痛明显,影响睡眠。次日清晨,症状开始缓解,患者自行停服吲哚拉 Patient: Female, 43a. Because of rheumatoid arthritis, in the past often take enteric-coated aspirin tablets, on November 20, 1991 after breakfast with indolane capsules 300mg (Shenyang Pharmaceutical Co., No. 910603), about 10min after lunch and Serve 300mg, feeling slightly tight upper body tight wrinkles, 1h after the symptoms have increased, did not attract attention. After dinner, taking indolazine again 300mg, about 0.5h, the whole body skin began to bursts tight, sweating, limb muscle acid sleepy discomfort. Followed by systemic skin sensitization, tenderness significantly affect sleep. The next morning, the symptoms started to ease and the patient stopped taking indolase on his own