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AIM:To investigate normal value range of low-frequent repeated nerve stimulation(RNS):whether different low-frequent stimulation and different muscles have different normal value range.METHODS:Low-frequent (3c /s and 5c /s)RNS of 30healthy people and 27myasth enia gravis(MG)patients were test.RESULTS:Superior limit of amplitude of wave a ttenuation value of low-frequent RNS(x±2.5s)of different muscles(orbicularis oculi muscle,deltoid muscle and abductor muscle of little finger)of healthy people was 5.45%-7.55%.According to our normal value standard,RNS positive rate of MG group was 85%;according to the current criteria(amplitude of wave attenuation value >10%),positive rate of MG group was 70%,th ere was no apparent difference in RNS positive rate(P>0.1).Some labs adopted the criteria that amplitude of wave attenuation value >15%,ac-cording to this criteria,positive r ate of MG group was 51%.Compared with positive rate(85%)obtained according to our criteria,there was apparent difference(P<0.01).CONCLUSION:Each labs should establish their own normal value standard according to difference muscle and different f re-quent.If adopt universal standard,amplitude of wave attenuation value8%or 10%was suggested.
A investigate: To investigate normal value range of low-frequent repeated nerve stimulation (RNS): whether different low-frequent stimulation and different muscles have different normal value range. METHODS: Low-frequent (3c / s and 5c / s) RNS of 30 heathy people and 27myasth enia gravis (MG) patients were test.RESULTS: Superior limit of amplitude of wave a ttenuation value of low-frequent RNS (x ± 2.5s) of different muscles (orbicularis oculi muscle, deltoid muscle and abductor muscle of little finger ) of healthy people was 5.45% -7.55% .According to our normal value standard, RNS positive rate of MG group was 85%; according to the current criteria (amplitude of wave attenuation value> 10%), positive rate of MG group was 70%, th ere was no apparent difference in RNS positive rate (P> 0.1). Home labs adopted the criteria that amplitude of wave attenuation value> 15%, ac- cording to this criteria, positive rote of MG group was 51% Compared with positive rate (85%) obtained according to our criteria, there was apparent differ ence (P <0.01) .CONCLUSION: Each labs should establish their own normal value standard according to difference muscle and different f re-quent.If adopt universal standard, amplitude of wave attenuation value8% or 10% was suggested.