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目的:分析胎儿中晚孕期产前超声筛查胎儿畸形的临床价值。方法:选取我院2011年1月到2013年1月间胎儿早孕期超声检测正常孕妇1240例,于胎儿中孕期(孕21~25周)和晚孕期(孕31~35周)各再进行一次超声检测工作,用Excel表进行统计分析,分类归纳统计胎儿畸形分类及各类畸形超声检出时间。结果:1240例胎儿早期超声检测正常孕妇中,胎儿中孕期检测显示胎儿畸形16例,检出率1.3%;其中中枢神经畸形3例,心脏畸形1例,前腹壁畸形2例,泌尿系统畸形1例,骨骼以及四肢畸形2例,双胎畸形2例,消化系统畸形2例,胎儿肿瘤1例,胎儿水肿1例,指趾异常1例,胎儿晚孕期检测显示有畸形3例,检出率为0.24%,分别为面部畸形1例,指趾异常1例,心脏畸形1例。这19例胎儿均证实为畸形胎儿。胎儿中孕期漏诊3例,漏诊率15.8%(3/19)。结论:超声检查是产前诊断胎儿畸形的重要诊断方法,诊断率高,安全性大,但部分胎儿畸形在中孕期超声仍未能诊断,所以对胎儿晚孕期再次行超声筛查工作,尤其注意对胎儿颜面部、心脏,颅脑,四肢等器官仔细的扫描,可有效提高畸形胎儿检测率,减少相应畸形的漏诊,为产科医生临床确诊和处理提供有效参考,具有极高的临床价值,同时可减少出生缺陷的发生,配合国家人口系统完成出生缺陷一级预防工作。
Objective: To analyze the clinical value of fetal prenatal ultrasound in fetus fetus malformation. Methods: A total of 1240 normal pregnancies were detected by ultrasonography during the first trimester of pregnancy from January 2011 to January 2013 in our hospital. The fetuses were re-performed in the second trimester of pregnancy (from 21 to 25 weeks of gestation) and from the third trimester of pregnancy (from 31 to 35 weeks of gestation) Ultrasound testing, statistical analysis using Excel tables, classification and classification of fetal malformations classification and all kinds of abnormal ultrasound detection time. Results: Among 1240 fetuses with normal early pregnancy, fetus deformity was detected in 16 pregnant women with the detection rate of 1.3%. Among them, 3 were central nervous deformities, 1 was cardiac malformations, 2 were anterior abdominal wall malformations and urinary malformations were 1 Cases, skeletal and limb deformities in 2 cases, twin deformities in 2 cases, 2 cases of digestive system malformations, 1 case of fetal tumors, 1 case of fetal edema, finger anomalies in 1 case, the fetus in the third trimester pregnancy test showed deformity, the detection rate 0.24%, respectively, 1 case of facial deformity, 1 case of abnormal digit toe and 1 case of cardiac malformation. All 19 cases of fetal confirmed abnormal fetal. Miscarriage during pregnancy in 3 cases, misdiagnosis rate of 15.8% (3/19). Conclusion: Ultrasonography is an important diagnostic method for prenatal diagnosis of fetal malformations. The diagnosis rate is high and the safety is high. However, some fetal malformations have not yet been diagnosed in the second trimester. Therefore, it is necessary to pay special attention to ultrasound screening in the late pregnancy Careful scanning of fetus facial, heart, brain, limbs and other organs can effectively improve the detection rate of malformation fetus, reduce the misdiagnosis of the corresponding deformity, provide effective reference for clinical diagnosis and treatment of obstetricians, with high clinical value, at the same time Can reduce the birth defects, with the national population system to complete a primary prevention of birth defects.