早产是当前围产儿死亡的主要原因 ,据统计早期婴儿死亡中约75 %与早产有关。早产儿中有约15%死于新生儿期 ,其死亡率比足月产儿高11～16倍 ,幸存的早产儿中尚有8 %左右出现智力障碍等神经系统后遗症。因此 ,做好早产的预测与预防是降低围产儿死亡率和提高新生儿质量的主要措施 Premature delivery is the leading cause of death in perinatal labor and it is estimated that about 75% of early infant deaths are associated with premature birth. About 15% of premature infants die in the neonatal period, with 11-16 times more likely to die than full-term infants and about 8% of surviving preterm infants have neurological sequelae such as mental retardation. Therefore, the prediction and prevention of premature delivery is the main measure to reduce perinatal mortality and improve newborn’s quality