目的探讨经前纵裂入路切除鞍区肿瘤术后并发症的特点及防治措施。方法回顾性分析76例鞍区肿瘤经前纵裂入路手术病例术后并发症的发生情况。结果本组76例经前纵裂入路显微外科切除术,其中肿瘤全切56例(73.7%),次全切除14例(18.4%),大部分切除6例(7.9%);术后尿崩症21例(27.6%)、电解质紊乱17例(22.3%)、癫痫5例(6.6%)、垂体功能低下3例(3.9%)、术后额叶脑内血肿2例(2.6%)、高热1例(1.3%)、应激性溃疡1例(1.3%),经积极处理后绝大多数并发症得到控制,2例严重的并发症(1例为水电解质紊乱,1例为消化道出血)未能控制;术后死亡2例(2.6%)。结论鞍区肿瘤经前纵裂入路术后并发症以水、电解质紊乱最为常见,术前认真准备、术中细致操作、术后积极观察处理,术后并发症基本上可以恢复。 Objective To investigate the characteristics and prevention and treatment of postoperative complications of resection of sellar region by means of anterior longitudinal splitting. Methods A retrospective analysis of 76 cases of sellar tumors of the preoperative longitudinal approach operation cases of postoperative complications. Results 76 cases (73.7%) underwent microsurgical resection of the anterior longitudinal splitting approach, 14 cases (18.4%) underwent subtotal resection and 6 cases (7.9%) underwent resection. 21 (27.6%) had diabetes insipidus, 17 (22.3%) had electrolyte disturbance, 5 (6.6%) had epilepsy, 3 had hypopituitarism (3.9%), and 2 had postoperative frontal lobe intracerebral hemorrhage , 1 case of fever (1.3%), and 1 case of stress ulcer (1.3%). Most of the complications were controlled after active treatment, and 2 cases of severe complications (one case of water and electrolyte imbalance and one case of digestion Road bleeding) failed to control; postoperative death in 2 cases (2.6%). Conclusions The postoperative complications of sellar tumor in the anterior longitudinal splitting approach are the most common complications of water and electrolytes. They are carefully prepared before operation, meticulous operation during operation, and actively observed and treated postoperatively. The postoperative complications can be basically recovered.