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目的:探讨卡铂瘤内注射结合支气管动脉灌注治疗晚期非小细胞肺癌的可行性及临床价值。方法:将卡铂经皮穿刺注入瘤内结合支气管动脉内灌注化疗药物治疗15例Ⅲ、Ⅳ期非小细胞肺癌,通过影像学、组织学、行为状况、生存期及并发症等指标观察。结果:完全缓解2例,部分缓解10例,稳定3例,无恶化,有效率80%。无严重并发症。结论:瘤内注射是一种安全、有效的给药途径,与BAI结合在提高晚期肺癌的近期疗效、改善生存质量、延长生存期方面有显著疗效
Objective: To investigate the feasibility and clinical value of carboplatin combined with bronchial arterial infusion in the treatment of advanced non-small cell lung cancer. METHODS: Carboplatin was intradermally injected into the tumor and intrabronchial arterial infusion chemotherapy was used to treat 15 cases of stage III and IV non-small cell lung cancer. The imaging, histology, behavior, survival and complications were observed. Results: Complete remission in 2 cases, partial remission in 10 cases, stable in 3 cases, no deterioration, 80% efficiency. No serious complications. Conclusions: Intratumoral injection is a safe and effective route of administration. Combined with BAI, it has a significant effect in improving the short-term efficacy, improving the quality of life, and prolonging the survival of advanced lung cancer.