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目的:探讨泪道塞在LASIK术后早期对干眼症状的影响。方法:随机选取在我院接受LASIK手术的患者54例108眼,其中27例54眼术后第2d植入诊断性泪道塞,另外27例54眼给予倍然眼药水点眼,于术后2wk进行泪液分泌试验(SchirmerⅠtest,SⅠt)、泪膜破裂时间(breaking-uptime,BUT)和荧光素染色(FL)评分。结果:泪道塞组与倍然组泪液分泌实验结果分别为11.90±4.20,10.85±3.42mm/5min,两组间差异无统计学意义(P>0.05)。泪道塞组与倍然组BUT分别为13.12±2.58和11.67±3.29s,两组间无统计学差异(P>0.05)。泪道塞组与倍然组FL评分分别为6.23±1.12和5.42±2.10分,差异无统计学意义(P>0.05)。结论:泪道塞在LASIK术后早期缓解干眼症状中与人工泪液具有相同的作用。
Objective: To investigate the effect of lacrimal passage on symptoms of dry eye early after LASIK. Methods: A total of 108 eyes of 54 patients were enrolled in this study. Among them, 54 of 54 eyes were diagnosed with lacrimal duct plug on the 2nd day postoperatively, and 27 cases of 54 eyes were treated with double eye drops. After 2 weeks Schirmer I test, SIt, breaking-up time (BUT) and fluorescein staining (FL) scores were performed. Results: The results of tear secretion in lacrimal passage group and triplicate group were 11.90 ± 4.20,10.85 ± 3.42mm / 5min, respectively. There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups in terms of BUT (13.12 ± 2.58 and 11.67 ± 3.29s, respectively) (P> 0.05). There were no significant differences in FL score between lacrimal plug group and triplicate group (6.23 ± 1.12 vs 5.42 ± 2.10, respectively) (P> 0.05). CONCLUSIONS: Lacrimal plugs have the same effect as artificial tears in relieving dry eye symptoms early after LASIK.