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目的 探讨间苯三酚在潜伏期对解除宫颈痉挛、消除宫颈水肿和促进宫口扩张的作用。 方法 选择正常足月妊娠临产后潜伏期≥8 h产程无进展的初产妇250 例,将其按随机表分成五组,每组各50例,即阿托品组、间苯三酚组(1 组、2 组、3 组和4 组)。分别给予宫颈局部注射阿托品0.5 mg、间苯三酚40 mg(1组)及宫颈局部注射或/和静脉分别注射间苯三酚160 mg、200 mg(2 组、3组、4组)。 结果 间苯三酚组平均宫口扩张速度为(2.82±1.82)cm/h,第一产程平均时间(14.23±1.11)h;阿托品组分别为:(1.78±1.01)cm/h和(17.71±2.23) h,有显著差异(P<0.01)。 结论 潜伏期宫颈局部注射或/和静脉注射间苯三酚对加速宫口扩张、缩短产程、降低难产率有一定的临床意义。
Objective To investigate the effect of phloroglucinol in relieving cervical spasm, eliminating cervical edema and promoting cervical dilatation in the incubation period. Methods Select 250 cases of primiparae who had no progress in normal full-term pregnancy ≥8 h after birth and were randomly divided into five groups, 50 cases in each group, namely atropine group, phloroglucinol group (group 1, 2 Group, group 3 and group 4). Atropine 0.5 mg, 40 mg (group 1) of phloroglucinol and 160 mg of phloroglucinol 200 mg (group 2, group 3 and group 4) were injected into the cervix. Results The average rate of uterine cervix expansion in phloroglucinol group was (2.82 ± 1.82) cm / h and the average time of the first stage of labor was (14.23 ± 1.11) h. The atropine group was (1.78 ± 1.01) cm / h and (17.71 ± 2.23) h, there was a significant difference (P <0.01). Conclusion The latent period of cervical intraepithelial injections and / or intravenous phloroglucinol has some clinical significance in accelerating the dilatation of uterine cervix, shortening labor and decreasing the rate of dystocia.