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对３８例危重病人并发多系统器官功能衰竭（ＭＯＳＦ）进行了回顾分析，并探讨了伍用大剂量维生素Ｃ（ＶＣ）治疗的可能性。本组病人ＭＯＳＦ的发生器官以肾、肝、心和外周循环发生率最高，其次为肺及消化、神经和凝血系统。ＶＣ治疗组２０例ＭＯＳＦ死亡９例（４５％），对照组１８例死亡１２例（６６．７％）。两组比较前者死亡率低于对照组（Ｐ≤０．０５）。本文结果表明，在综合治疗ＭＯＳＦ的基础上应用大剂量ＶＣ具有一定价值。
A retrospective analysis was performed on 38 cases of critically ill patients complicated with multisystem organ failure (MOSF) and to explore the possibility of treatment with high-dose vitamin C (VC). The occurrence of MOSF organ in this group of patients with kidney, liver, heart and peripheral circulation the highest incidence, followed by lung and digestive, nervous and coagulation system. Nineteen patients (45%) died of MOSF in VC group and 12 patients (66.7%) died in control group. The mortality rate of the former two groups was lower than that of the control group (P≤0.05). The results show that the application of large doses of VC on the basis of comprehensive treatment of MOSF has some value.