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目的探讨各种不同的治疗方法对急性百草枯中毒的疗效。方法将2000年1月1日～2008年12月31日确诊的60例急性百草枯中毒入选患者分成三组,每组20例,A组为常规治疗,B组为常规治疗加血液灌流治疗,C组为常规治疗加血液灌流加血必净注射液治疗。观察患者肝、肾功能,心肌酶谱,血气分析,死亡率等指标的变化。结果C组患者的肝、肾功能、心肌酶谱、血气分析、死亡率等的指标明显优于B组,而B组患者的各项指标又优于A组。结论应用血必净注射液联合血液灌流及常规治疗,可以减轻百草枯中毒患者各个器官的损害,抑制肺纤维化,降低患者的死亡率。
Objective To explore the curative effect of different kinds of treatment on acute paraquat poisoning. Methods Sixty patients with acute paraquat poisoning who were diagnosed from January 1, 2000 to December 31, 2008 were divided into three groups of 20 cases each. Group A received routine treatment, group B received conventional therapy plus hemoperfusion, C group for routine treatment plus hemoperfusion plus Xuebijing injection treatment. Observation of liver, kidney function, myocardial enzymes, blood gas analysis, mortality and other indicators of change. Results The indexes of liver, renal function, myocardial zymogram, blood gas analysis and mortality in group C were better than those in group B, and those in group B were better than those in group A. Conclusion Xuebijing injection combined with hemoperfusion and routine treatment can alleviate the damage of various organs of paraquat poisoning patients, inhibit pulmonary fibrosis and reduce the mortality of patients.