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目的探讨肝脾CT值比值与扩散加权成像ADC值的相关性,研究扩散加权成像ADC值对脂肪肝患者的严重程度分级的可行性。方法回顾性收集在我院影像科检查的患者80例,所有的患者均行CT和MRI扫描,包括正常对照组(n=20)、轻度脂肪肝组(n=20)、中度脂肪肝组(n=20)及重度脂肪肝组(n=20)。通过分析肝脾CT值比值与ADC值的相关性及比较四组样本的ADC值间的差异来评估ADC值对脂肪肝患者的严重程度分级的可行性。以P<0.05认为差异具有显著统计学意义。结果肝脾的CT值比值与ADC值之间存在显著的正相关(r=0.954,P<0.05);肝实质的平均A D C值:正常肝实质(1.451±0.123)×10~(-3)mm~2/sec,轻度脂肪肝(1.341±0.014)×10~(-3)mm~2/sec,中度脂肪肝(1.206±0.007)×10~(-3)mm~2/sec,重度脂肪肝(1.040±0.017)×10~(-3)mm~2/sec,组间比较差异均具有显著的统计学意义(P<0.05)。结论肝脾CT值比值与ADC值具有显著正相关性,ADC值对肝细胞脂肪变性的严重程度分级诊断是可行的。
Objective To investigate the correlation between CT value of liver and spleen and ADC value of diffusion-weighted imaging and to investigate the feasibility of diffusion-weighted imaging ADC value grading of severity of patients with fatty liver. Methods Totally 80 patients were examined retrospectively in our department. All patients underwent CT and MRI scans, including normal control group (n = 20), mild fatty liver group (n = 20), moderate fatty liver Group (n = 20) and severe fatty liver group (n = 20). The feasibility of grading the severity of fatty liver patients by ADC value was evaluated by analyzing the correlation between CT value of liver and spleen and ADC value and comparing the ADC value of four samples. P <0.05 considered the difference was statistically significant. Results There was a significant positive correlation between CT value and ADC value of liver and spleen (r = 0.954, P <0.05). Mean ADC value of liver parenchyma: normal liver parenchyma (1.451 ± 0.123) × 10 ~ (-3) mm Moderate fatty liver (1.206 ± 0.007) × 10 -3 mm 2 / sec, mild fatty liver (1.341 ± 0.014) × 10 -3 mm 2 / sec, Fatty liver (1.040 ± 0.017) × 10 ~ (-3) mm ~ 2 / sec had significant difference between the two groups (P <0.05). Conclusion The CT value of liver and spleen has a significant positive correlation with ADC value, and the ADC value is feasible for grading the severity of steatosis.