为了解决在设计和ＧＭＰ验收实践中遇到的不同洁净度级别洁净室之间是否要设缓冲室的问题，通过理论计算说明了缓冲室的作用和应具有的概念，指出了设置缓冲室的各种具体条件，进而给出了缓冲室的设计方法和原则。 In order to solve the problem of whether or not to set the buffer chamber between clean rooms of different cleanliness levels encountered in the design and GMP acceptance practices, the role of the buffer chamber and the concepts that should be possessed are explained through theoretical calculations, and each of the buffer chambers is specified. The specific conditions, and then give the design method and principle of the buffer chamber.