Polydimethylsiloxane (PDMS)-polystyrene (PS) interpenetrating polymer network (IPN) was prepared and characterized by FTIR, TGA, WCA, swelling experiments, and SEM. The IPN was used for pervaporation (PV) recovery of butanol. Both the permeation flux and separation factor increased with feed temperature, and both water and butanol fluxes increased with feed concentration, while no obvious effect of concentration on separation factor was found. Through the forma-tion of IPN structure, the total flux of PDMS-PS IPN pervaporation membrane increased greatly with the decrease of separation factor. At the feed temperature of 60℃, the IPN membrane obtained a total flux of 920.3 g/m2h with a separation factor of 9.5.