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作者对48例男孩单侧或双侧隐睾症者进行双盲对照试验,以评价鼻内应用合成黄体化激素释放激素(简称LHRH)的效果。方法:年龄1 1/2～12岁有单侧或双侧隐睾症的健康男孩,即睾丸在腹股沟管外环和阴囊颈之间扪及或完全不能扪及者,过去均未接受隐睾症的治疗,睾丸可回缩者不包括在内。84例随机分为治疗及对照两组。用LHRH水溶液(1毫克/毫升)或安慰剂喷入两侧鼻孔,每日6次(在早、中、晚饭前后,每次间隔30～60分钟),估计每日LHRH剂量为1.2毫克。
The authors conducted a double-blind controlled trial in 48 boys with unilateral or bilateral cryptorchidism to evaluate the effectiveness of intranasal administration of synthetic LHRH. Methods: A healthy boy aged 1 1/2 to 12 years old with unilateral or bilateral cryptorchidism, testis in the inguinal canal between the outer ring and the scrotum neck palpable or not palpable at all, in the past have not accepted cryptorchidism Symptoms of treatment, testicular retraction are not included. 84 cases were randomly divided into treatment and control groups. The LHRH dose (1 mg / mL) or placebo was injected into both nostrils six times a day (30-60 minutes before, during, and after dinner) and an estimated LHRH dose of 1.2 mg daily.