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通过对20例慢性鼻窦炎功能性内窥镜鼻窦手术前后的鼻窦粘膜进行了扫描电镜和透射电镜观察。结果发现:术前上皮结构紊乱,细胞表面纤毛断裂、倒伏、脱落,细胞内线粒体减少;鳞状上皮化生,纤维组织增生;杯状细胞增多,上皮下炎性细胞浸润。术后上皮细胞排列整齐,纤毛再生,细胞内线粒体增多,杯状细胞减少。作者认为,慢性鼻窦炎是由于窦口鼻道复合体阻塞,通气引流障碍所引起;功能性内窥镜鼻窦手术能解除阻塞,使窦内氧分压增高,从而使鼻窦粘膜恢复正常形态;组织形态学研究用于鼻窦手术后的疗效评价,不失为一种客观的方法。
20 cases of chronic sinusitis functional endoscopic sinus surgery before and after the sinus mucosa scanning electron microscopy and transmission electron microscopy. The results showed that: preoperative epithelial structure disorders, cell surface cilia rupture, lodging, fall off, mitochondria decreased; squamous metaplasia, fibrous tissue proliferation; goblet cells increased subepithelial inflammatory cell infiltration. After epithelial cells arranged neatly, cilia regeneration, intracellular increase in mitochondria, goblet cells decreased. The authors believe that chronic sinusitis is caused by the obstruction of the ostiomeatal complex, ventilation and drainage disorders caused by functional endoscopic sinus surgery can unblock the sinus partial pressure of oxygen increased, so that sinus mucosa returned to normal form; tissue Morphological studies for the evaluation of the efficacy of sinus surgery may well be an objective method.