论文部分内容阅读
一次静脉注射12.5mg/kg。bw的盐酸吗啡染毒雄性S-D大鼠,2小时后处死,取其脑、肾、肝、肺、心组织以2%戊二醛和4%多聚甲醛混合液固定后,常规石蜡切片。运用抗吗啡抗血清及SABC技术染色。结果显示上述组织切片有不同程度的阳性染色,阳性着色主要见于肾髓质部分肾小管上皮细胞,肝脏中央静脉周围的肝细胞、肺泡上皮细胞及肺内小支气管粘膜上皮细胞、中脑部分神经细胞、室管膜细胞、心肌细胞.以及各器官小血管及毛细血管内皮细胞胞浆、血浆及肾小管腔内尿液。
A single intravenous injection of 12.5mg / kg. bw morphine injection male S-D rats were killed after 2 hours, the brain, kidney, liver, lung, heart and heart tissue was fixed with a mixture of 2% glutaraldehyde and 4% paraformaldehyde, conventional paraffin sections . Using anti-morphine antiserum and SABC technology staining. The results showed that the above-mentioned tissue sections were positive staining to varying degrees, the positive staining mainly found in renal medullary renal tubular epithelial cells, the liver around the central vein of the liver cells, alveolar epithelial cells and lung bronchial epithelial cells, midbrain nerve cells , Ependymal cells, cardiomyocytes. As well as various organs of small blood vessels and capillary endothelial cells cytoplasm, plasma and renal tubular lumen urine.