九十年代以来 ,随着移植免疫学、免疫药理学等相关学科的飞速发展 ,人们开发出一些新型免疫抑制药物用于肾移植。动物实验及某些Ⅲ期临床实验已证明这些免疫抑制剂能显著降低肾移植后急性排斥反应发生率 ,其中一些药物尚有防治慢性排斥反应的作用 ,而且感染和恶性肿瘤的发病率 Since the nineties, with the rapid development of related disciplines such as immunology and immunopharmacology, some new immunosuppressive drugs have been developed for kidney transplantation. Animal experiments and some Phase III clinical trials have shown that these immunosuppressive agents can significantly reduce the incidence of acute rejection after kidney transplantation, some of which are still the role of prevention and treatment of chronic rejection, and the incidence of infection and malignancy