论文部分内容阅读
本文用放射免疫分析( R I A) 法检测了41 例急性心肌梗塞( A M I) 患者血清中的甲状腺激素( T T3 , T T4 , T S H, F T3 , F T4) 水平, 并与正常人及 A M I患者的肌钙蛋白 T( Tn T) 含量进行了比较。结果表明:41 例急性心肌梗塞患者的甲状腺激素中 T T3 及 F T3 水平分别为0 .94 ±0 .40ng/m L 和1 .09 ±0 .57pg/m L,与37 例正常对照组( T T3 为1 .73 ±0 .31ng/ m L, F T3 为3 .12 ±0 .75pg/m L) 均有高度显著性差异( P< 0 .01) 。动态观察甲状腺激素水平在 A M I 患者溶栓治疗过程中的变化表明: T T3 及 F T3 水平随着 A M I治疗的进行和病情的稳定慢慢增加及至正常, 与诊断 A M I的“金标准” Tn T 呈高度负相关( r1 = - 0 .7998 ,r2 = - 0 .7858) 。研究提示: 急性心肌梗塞患者血清甲状腺激素水平分析可用于 A M I的辅助诊断。连续动态观察还可为 A M I患者的疗效观察及预后判断提供切实的参考依据。
The levels of thyroid hormones (T T3, T T4, T S H, F T3, F T4) in serum of 41 patients with acute myocardial infarction (A M I) were measured by radioimmunoassay (RIA) Troponin T (Tn T) levels in normal subjects and A M I patients were compared. The results showed that the thyroid hormones in 41 patients with acute myocardial infarction were T 0 and T T3, respectively. 94 ± 0. 40 ng / m L and 1. 09 ± 0. 57pg / m L and 37 normal controls (1.73 ± 0.31ng / m T at T T3 and 3.12 ± 0.75 pg / m L at F T3) (P <0 .01). Dynamic observation of thyroid hormone levels in patients with A M I during thrombolytic therapy changes showed that: T T3 and F T3 levels with the A M I treatment and the stability of the disease slowly increased to normal, and the diagnosis of A M I “ Gold standard ”Tn T was highly negatively correlated (r1 = -0.7998, r2 = -0.7858). Study suggests that: serum thyroid hormone levels in patients with acute myocardial infarction can be used for the auxiliary diagnosis of A M I. Continuous dynamic observation can also provide a practical reference for the observation and prognosis of A M I patients.