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目的观察抗结核病药物固定复合制剂(FDC)治疗高原地区肺结核的疗效。方法我省2010年6月份在海东地区开始试点用抗结核病药物FDC治疗肺结核患者,用病历回顾方法对2009年中使用抗痨板式患者和FDC药物疗效进行比较分析。结果观察组与对照组比较,观察组症状改善率明显高于对照组;观察组阴转率高于对照组;治疗的依从性观察组较对照组高;不良反应对照组高于观察组;>50岁患者观察组不良反应明显较对照组低,且差异有统计学意义。结论 FDC抗痨药物治疗肺结核比板式药物不良反应小,患者依从性好,尤其对老年人不良反应低。
Objective To observe the curative effect of anti-tuberculosis drug-fixing compound (FDC) in the treatment of tuberculosis in the plateau area. Methods In June 2010, our province began pilot treatment of tuberculosis patients with anti-tuberculosis drug FDC in Haidong region. The medical records were used to compare the efficacy of anti-tuberculosis patients and FDC in 2009. Results Compared with the control group, the improvement rate of symptoms in the observation group was significantly higher than that in the control group; the negative conversion rate in the observation group was higher than that in the control group; the treatment compliance group was higher than the control group; the adverse reaction control group was higher than the observation group; Adverse reactions in the 50-year-old patient group were significantly lower than those in the control group, and the difference was statistically significant. Conclusion FDC anti-tuberculosis drug treatment of tuberculosis than the small adverse drug reactions, patients with good compliance, especially for the elderly with low adverse reactions.