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目的稳定型心绞痛(SA)与不稳定型心绞痛(UA)药物治疗的差异及临床意义。方法 180例进行心绞痛治疗的患者,根据表现类型不同分为稳定组和不稳定组,各90例。两组患者均采用美托洛尔治疗。比较两组患者心绞痛、心电图和中医证候总有效率。结果稳定组心绞痛、心电图和中医证候总有效率分别为71.11%、67.78%和73.33%,不稳定组分别为87.78%、85.56%和90.00%。不稳定组心绞痛、心电图和中医证候总有效率均高于稳定组,差异具有统计学意义(P<0.05)。结论美托洛尔胶囊更适合于UA,可以有效降血脂,改善心电图,缓解心绞痛症状,提高中医证候积分,值得在UA中推广使用。
Objective To investigate the difference and clinical significance of drug therapy between stable angina pectoris (SA) and unstable angina pectoris (UA). Methods One hundred and eighty patients undergoing angina pectoris were divided into stable group and unstable group according to different types of manifestations, 90 cases in each group. Metoprolol was used in both groups. The total effective rate of angina pectoris, electrocardiogram and TCM syndromes were compared between the two groups. Results The total effective rates of angina pectoris, electrocardiogram and TCM syndrome in stable group were 71.11%, 67.78% and 73.33% respectively, while those in unstable group were 87.78%, 85.56% and 90.00% respectively. The total effective rate of unstable angina pectoris, electrocardiogram and TCM syndromes in stable group were significantly higher than those in stable group (P <0.05). Conclusion Metoprolol capsule is more suitable for UA, which can effectively reduce blood fat, improve electrocardiogram, relieve angina pectoris and improve TCM syndrome score, which is worth popularizing in UA.