肿瘤化疗药物渗漏可致局部皮肤肿胀、烧灼样痛、水疱、静脉炎甚至组织坏死,严重者须外科清创植皮。损伤程度一般分为局部组织炎性反应期、静脉炎性反应期和组织坏死期。按照渗漏后对组织的刺激程度,可将化疗药物分为发疱剂、刺激剂和非刺激剂。一旦发生药液渗漏,应立即停药,抽吸血管内外药液,及早给予冷敷、热敷、药物湿敷等处理,以避免发生更严重的并发症。加强患者及其家属的安全用药教育、正确掌握给药方法是预防化疗药物渗漏的重要措施。 Tumor chemotherapy drug leakage can cause local skin swelling, burning pain, blisters, phlebitis and even tissue necrosis, severe surgical skin graft debridement. The degree of injury is generally divided into local tissue inflammatory response, phlebitis and tissue necrosis. In accordance with the level of tissue irritation after chemotherapy, chemotherapy drugs can be divided into blisters, stimulants and non-stimulants. In the event of liquid leakage, should be immediately discontinued, drawing blood vessels inside and outside the liquid, as early as cold, hot compress, drug wet compress and other treatment to avoid more serious complications. Strengthen patient and family members of the safe drug education, proper control of drug delivery is an important measure to prevent the leakage of chemotherapy drugs.