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最近在伦敦宣布一种新型的胶囊剂和液体剂的药物释放系统已在欧洲应用。这种称之为Pennkinetic药物释放系统是第一个能够使药物从液体控制释放的系统,且可持续十二小时。它包括一个带负电荷的惰性离子交换树脂聚合物以及制成具有正电荷的药物和树脂的复合物。然后此复合物再用半渗透乙基纤维素包衣。在摄取过程中,例如钠离子在胃肠道通过复合物外膜时,由于钠离子对树脂的亲和力比药物要大,故钠
Recently in London a new drug delivery system for capsules and liquids has been announced for use in Europe. The so-called Pennkinetic drug delivery system is the first system that can release drugs from liquids and lasts for 12 hours. It consists of a negatively charged, inert ion exchange resin polymer and a complex made of a positively charged drug and a resin. This complex is then coated with semi-permeable ethylcellulose. During ingestion, for example, when sodium ions pass through the outer membrane of the compound in the gastrointestinal tract, since the affinity of sodium ions for the resin is greater than that of the drug, sodium