红斑狼疮是一种系统性疾病,以免疫复合物的病理沉积为基本特征①②全身各系统各脏器均可受影响,但其程度不同,产生的危害性及后果也不一样。一般说来,对系统性红斑狼疮(SLE)患者生命威胁最大的是肾脏病变和感染。 SLE患者肾脏病变的发生率报告不一致,早期仅从临床来判断时,狼疮性肾炎的发生率约为45～75%。主要表现为尿蛋白、尿沉渣不正常和肾功能受损。一般认为,尿蛋白、尿沉渣和肾功能异常的程度与肾脏病变有一致关系,也就是说,尿蛋白、尿沉渣和肾 Lupus erythematosus is a systemic disease that takes the pathological deposition of immune complexes as its basic feature. ① All organs of the whole body can be affected by various organs. However, the degree of lupus is different, and their harmfulness and consequences are also different. In general, the most life threatening patients with systemic lupus erythematosus (SLE) are kidney lesions and infections. The incidence of renal disease in patients with SLE reported inconsistent, early only from clinical judgment, the incidence of lupus nephritis is about 45 to 75%. Mainly for urinary protein, urinary sediment is not normal and impaired renal function. It is generally believed that urinary protein, urinary sediment and renal dysfunction levels and renal disease have a consistent relationship, that is, urinary protein, urinary sediment and kidney