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目的 评估放免显像在大肠癌诊断中的价值。方法 采用改良氯胺T法对抗癌胚抗原 (CEA)单抗进行13 1Ⅰ标记 ,将碘标记后的单抗静脉注射到患者体内 ,48～ 72小时后行单光子发射型计算机辅助断层仪 (SPECT)显像 ,图像采用免疫断层专用程序重建 ,检查前后检测血相关指标。结果 45例行放免导向诊断的患者 ,44例得到确诊 ,诊断准确率 97 8%。除 5例病人有一过性发热外 ,余均无不良反应。结论 放免显像在大肠癌的诊断、分期以及术后监测上具有较高价值 ,且安全性好。
Objective To evaluate the value of RIA in the diagnosis of colorectal cancer. Methods Chlamydomonas reinhardtii (CEA) monoclonal antibody was labeled with 131I by modified chloramine T method. Iodinated monoclonal antibody was injected intravenously into the patient. After 48 to 72 hours, single photon emission computed tomography SPECT) imaging, the image reconstruction using immune-specific procedures, before and after testing to detect blood-related indicators. Results Of the 45 patients who underwent radiotherapy-guided diagnosis, 44 patients were diagnosed with a diagnostic accuracy rate of 97.8%. In addition to 5 patients had transient fever, I have no adverse reactions. Conclusion Radiofrequency imaging in the diagnosis of colorectal cancer, staging and postoperative monitoring has high value, and good safety.