翼状胬肉是仅见于人类的常见的眼表疾病之一。但至今有关翼状胬肉的病因及发病机制仍无统一的定论。本文对翼状胬肉与肿瘤相关的发病机制研究进展作一综述。1杂合性丢失及微卫星不稳定性与翼状胬肉翼状胬肉最近被发现具有许多肿瘤样特性,包括轻度发育不良,局部的浸润性和高复发 Pterygium is seen in humans only one common ocular surface disease. However, the etiology and pathogenesis of pterygium so far still no uniform conclusion. This article reviews the progress of the pathogenesis of pterygium and tumor. Loss of heterozygosity and microsatellite instability with pterygium Pterygium has recently been found to have many tumor-like properties, including mild dysplasia, localized invasiveness, and high recurrence