咽喉反流症(LPR)是反流性食管病的一种类型,由于酸碱反流导致咽喉黏膜破损,致发声障碍、慢性咳嗽、咽异物感、吞咽困难等。近年国内发病率有逐渐上升的趋势。笔者2000年6月~2006年6月,应用抑酸剂埃索美拉唑治疗LPR患者,取得较好效果。现根据患者的临床症状并结合纤维咽喉镜发现 Laryngeal reflux disease (LPR) is a type of reflux esophageal disease, due to acid reflux caused by pharyngeal mucosal damage, causing speech problems, chronic cough, pharyngeal foreign body sensation, dysphagia and so on. In recent years, the domestic incidence has gradually increased. The author from June 2000 to June 2006, the application of acid suppressive esomeprazole LPR patients, and achieved good results. According to the patient’s clinical symptoms combined with fibrolaryngoscope found