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目的:观察三黄屏风膏穴位贴敷防治小儿反复呼吸道感染的临床疗效,并探索其作用机理。方法:将240例符合纳入标准的患儿随机分为对照组和治疗组,对照组给予基础治疗(左旋咪唑片口服),治疗组给予基础治疗加三黄屏风膏穴位贴敷。结果:治疗后12个月两组总有效率比较,治疗组优于对照组,差异有统计学意义(P<0.05);治疗组中医证候积分低于对照组,差异有统计学意义(P<0.05);治疗后6、12个月Ig G、CD4/CD8比较,治疗组均高于对照组,差异有统计学意义(P<0.01);治疗后3、6、12个月PAF变化比较,治疗组均低于对照组差异有统计学意义(P<0.01)。结论:三黄屏风膏穴位贴敷防治小儿反复呼吸道感染临床疗效较好,可改善机体免疫球蛋白,调整T细胞亚群,提高患儿免疫力。
Objective: To observe the clinical curative effect of Sanhuang screen ointment sticking on prevention and treatment of recurrent respiratory tract infection in children, and to explore its mechanism of action. Methods: 240 eligible children were randomly divided into control group and treatment group. The control group was given basic treatment (levamisole tablets orally). The treatment group was given basic treatment plus Sanhuang screen cream paste. Results: The total effective rate of the two groups after 12 months of treatment was better than that of the control group (P <0.05), and the score of TCM syndromes in the treatment group was lower than that of the control group (P <0.05). Compared with the control group, the levels of Ig G and CD4 / CD8 in the treatment group were significantly higher at 6 and 12 months after treatment (P <0.01); PAF at 3, 6 and 12 months after treatment , The treatment group were lower than the control group, the difference was statistically significant (P <0.01). Conclusion: The application of Sanhuang Screen Gypsum Acupoint Application in Prevention and Treatment of Infantile Recurrent Respiratory Infection has a good clinical effect, which can improve the immunoglobulin, adjust the T cell subsets and improve the immunity of children.