最新的研究表明,噪声对听力的损伤不仅取决于外界噪声刺激的性质、强度和持续时间,而且体内因素以及内耳局部调节机制密切相关。本文综述近年来有关文献,讨论了物质代谢改变、神经内分泌改变以及一些相关因素协同作用对噪声性听损伤的影响。关于体内因素对噪声性听损伤影响的研究及噪声性聋防治提供了新的重要线索和理论依据,具有广泛应用前景。 Recent research shows that the damage of noise to hearing depends not only on the nature, intensity and duration of external noise stimuli, but also the in vivo factors and the local regulation mechanism of inner ear. This review summarizes the literature in recent years and discusses the effects of changes in metabolism, neuroendocrine changes and the synergistic effects of some related factors on noise-induced hearing impairment. The study on the influence of internal factors on noise-induced hearing impairment and noise control provide new important clues and theoretical basis, which has a wide range of applications.