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目的:探讨维吾尔族多囊卵巢综合征患者胰岛素抵抗与高雄激素血症的相关性。方法:回顾性分析2014年4月-2015年5月就诊于本院的58例维吾尔族PCOS患者的临床资料,将PCOS患者分为两组:胰岛素抵抗(IR)组28例,非胰岛素抵抗(NIR)组30例,比较两组的性激素水平、血糖、胰岛素以及胰岛素抵抗等指标。另外选择31例正常育龄期维吾尔族妇女作为对照组。结果:(1)维吾尔族PCOS患者T水平与对照组比较差异有统计学意义(P<0.001),维吾尔族PCOS患者的HA患病率为38%(22/58)。(2)IR组睾酮水平显著高于NIR组(P<0.05)。(3)PCOS组中IR与T呈正相关(P<0.05)。结论:高雄激素血症是维尔族PCOS患者的主要特征,维吾尔族PCOS患者的胰岛素抵抗与高雄激素血症之间呈显著正相关。
Objective: To investigate the relationship between insulin resistance and hyperandrogenism in Uighur women with polycystic ovary syndrome. Methods: The clinical data of 58 Uighur PCOS patients treated in our hospital from April 2014 to May 2015 were retrospectively analyzed. Patients with PCOS were divided into two groups: insulin resistance (IR) group (n = 28), non-insulin resistance NIR group of 30 cases, comparing the two groups of sex hormone levels, blood glucose, insulin and insulin resistance and other indicators. In addition, 31 normal Uighur women of childbearing age were selected as the control group. Results: (1) The T level of PCOS patients in Uygur nationality was significantly different from that in control group (P <0.001). The prevalence of HA in Uygur PCOS patients was 38% (22/58). (2) The level of testosterone in IR group was significantly higher than that in NIR group (P <0.05). (3) There was a positive correlation between IR and T in PCOS group (P <0.05). Conclusions: Hyperandrogenism is the main characteristic of PCOS patients with Vill, and there is a significant positive correlation between insulin resistance and hyperandrogenism in Uighur PCOS patients.