β catenin参与的Wnt信号传导途径是调控细胞生长增殖的重要途径。该途径参与调节一些和胚胎发育相关的基因转录 ,新近发现一些原癌基因和细胞周期调控因子基因也是该途径激活的靶基因。β catenin是该信号传导途径的关键分子 ,其在肿瘤发生中的作用倍受关注。此外 ,β catenin Wnt signaling pathway involved in β catenin is an important way to regulate cell growth and proliferation. This pathway is involved in the regulation of some gene transcription related to embryonic development. Recently, some proto-oncogenes and cell cycle regulatory factor genes have also been found to be target genes activated by this pathway. β catenin is a key molecule of this signal transduction pathway, and its role in tumorigenesis has drawn much attention. In addition, β catenin