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目的:建立梨状窝兔VXZ移植癌动物模型,从实验室角度探讨清瘤亮喉方对梨状窝VX2瘤兔的治疗效果。方法:建立梨状窝VX2瘤兔模型后,随机分为治疗组(清瘤亮喉方)、对照组(5-f嘧脲啶)、空白组,观察瘤兔的一般生命体征、生存率等,并结合解剖,观察清瘤亮喉方对梨状窝VX2瘤兔的治疗作用。结论:清瘤亮喉方与5-f嘧脲啶组对肿瘤的干预性与空白组存在显著差异;对早期瘤兔的干预性清瘤亮喉方组与5-f嘧脲啶组存在显著差异。清瘤亮喉方对中晚期梨状窝VX2瘤兔的治疗作用与5-f嘧脲啶组无明显差异。
OBJECTIVE: To establish an animal model of VXZ carcinoma in rabbits with pear-shaped rabbits, and to investigate the therapeutic effect of clearing tumor from the larynx to the VX2 tumor in rabbits from a laboratory perspective. Methods: The rabbits model of VX2 tumor was established. The rabbits were randomly divided into treatment group (Qinglianglianghu Decoction), control group (5-f-pyrimidine) and blank group, and observed the general vital signs and survival rate , And combined with anatomy to observe the Qinglianglv Fang on pear-shaped VX2 tumor rabbits treatment. Conclusion: There are significant differences between the tumor-clearing and laser-induced laryngotracheitis and the 5-f-pyrimidine group in tumor intervention group and the blank group. difference. Qingliangliangfang on the treatment of mid-late pear-shaped nest VX2 tumor rabbits and 5-f pyrimidine group no significant difference.