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为了寻找理想的血小板聚集抑制剂，设计合成了１４个６－（４－取代苯基）－４，５－二氢－３（２Ｈ）－哒嗪酮类化合物．ＡＤＰ诱导，家兔体外血小板聚集实验表明，均有不同程度的抑制作用，其中化合物（Ⅰ８）的作用最强．
In order to find an ideal inhibitor of platelet aggregation, 14 6- (4-substituted phenyl) -4,5-dihydro-3 (2H) -pyridazinones were designed and synthesized. ADP induced rabbit platelet aggregation test in vitro showed that there are different degrees of inhibition, of which compound (I8) the strongest.