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目的:探讨原始粒细胞对再生障碍性贫血(AA)、低增生性骨髓增生异常综合征(MDS)的鉴别诊断价值。方法:对9例AA和9例低增生性MDS进行分析。结果:AA患者的骨髓中均未出现原粒,差异有统计学意义(P<0.01),MDS患者的骨髓中,晚幼粒以上阶段细胞比例明显高于AA,并出现多个系统的病态造血。AA仅表现为粒、红、巨三系的减低或一系以上的减低。结论:原始粒细胞等的观察对AA、MDS的鉴别诊断有着重要意义。
Objective: To investigate the differential diagnosis value of primitive granulocyte to aplastic anemia (AA) and hypo-proliferative myelodysplastic syndrome (MDS). Methods: Nine cases of AA and nine cases of hypo-proliferative MDS were analyzed. Results: There was no significant difference in the bone marrow of patients with AA (P <0.01). The proportion of cells in the late stage of the late stage of MDS was significantly higher than that of the AA in the bone marrow of patients with MDS, and multiple systems of pathological hematopoiesis . AA showed only grain, red, giant reduction of three or more than one series. Conclusion: The observation of primitive granulocytes is of great significance for the differential diagnosis of AA and MDS.