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作者评估了短期抗生素治疗惠普尔病(Whipple’s disease,WD)的疗效。19例根据临床特征和小肠活检确诊为WD的患者接受平均为期7.9周(范围4～20周)的抗生素治疗:去甲基金霉素(600mg/d)14例,其中1例也服用氯霉素(2g/d),1例给予氨苄青霉素(2g/d)和4例给与羟氨苄青霉素(1.5g/d)。这些药物均连续使用8周。结果发现,在所有患者中,临床反应迅速、自我
The authors evaluated the efficacy of short-term antibiotics in the treatment of Whipple’s disease (WD). Nineteen patients diagnosed with WD on the basis of clinical characteristics and intestinal biopsy received an average of 7.9 weeks (range 4 to 20 weeks) of antibiotic treatment: 14 methotrexamycin (600 mg / d), 1 of which also received chloramphenicol (2 g / d), 1 ampicillin (2 g / d) and 4 amoxicillin (1.5 g / d). These drugs are used continuously for 8 weeks. The results showed that in all patients, the clinical response was rapid and self