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目的分析68例颅内动脉瘤或糖尿病致单侧动眼神经麻痹患者的临床特点及预后。方法回顾性分析单侧动眼神经麻痹68例患者的临床资料。其中,由颅内动脉瘤致动眼神经麻痹患者36例(动脉瘤组,35例接受手术治疗),糖尿病致动眼神经麻痹患者32例(糖尿病组)。比较两组临床特点及治疗后6个月的随访结果。结果与动脉瘤组相比,糖尿病组患者年龄较大(P<0.01),男性较多(P<0.01)。动脉瘤组患者完全性眼肌麻痹比例高于糖尿病组(P<0.01)。两组患者的发病部位(左侧/右侧)比较无统计学差异(P>0.05)。6个月后随访,糖尿病组患者预后好于动脉瘤组(P<0.01)。结论与颅内动脉瘤所致单侧动眼神经麻痹患者相比,糖尿病致单侧动眼神经麻痹患者的发病年龄较大,男性较多,以不完全性眼肌麻痹为主,预后较好。
Objective To analyze the clinical features and prognosis of 68 cases of intracranial aneurysms or diabetic patients with unilateral oculomotor nerve paralysis. Methods The clinical data of 68 patients with unilateral oculomotor nerve paralysis were retrospectively analyzed. Among them, 36 cases of oculomotor nerve paralysis caused by intracranial aneurysm (aneurysm group, 35 cases underwent surgical treatment) and 32 cases of diabetic ophthalmoplegia (diabetic group). The clinical characteristics of the two groups and the follow-up results after 6 months of treatment were compared. Results Compared with the aneurysm group, the diabetic patients were older (P <0.01) and more men (P <0.01). The proportion of complete ophthalmoplegia in the aneurysm group was higher than that in the diabetic group (P <0.01). The incidence of the two groups of patients (left / right) was no significant difference (P> 0.05). After 6 months follow-up, the prognosis of diabetic patients was better than that of aneurysms (P <0.01). Conclusion Compared with patients with unilateral oculomotor nerve paralysis caused by intracranial aneurysms, patients with unilateral oculomotor nerve palsy caused by diabetes have a relatively older age and more men with incomplete orbital ophthalmoplegia, with a better prognosis .