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目的分析糖尿病合并脂肪肝患者与单纯糖尿病患者的部分临床指标的差异及其特点。方法 153例单纯糖尿病无脂肪肝患者设为无脂肪肝组,148例糖尿病同时存在脂肪肝患者设为脂肪肝组。比较两组患者的部分临床指标差异。结果脂肪肝组患者的腰围(WC)、体质量指数(BMI)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆固醇(TC)、低密度脂蛋白(LDL)、甘油三酯(TG)、谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)、C肽、尿酸(UA)水平均高于无脂肪肝组,糖尿病病程短于无脂肪肝组,差异均具有统计学意义(P<0.05);两组患者的性别、年龄、空腹血糖(FPG)、糖化血红蛋白(Hb A1c)、总胆红素(TBIL)比较,差异均无统计学意义(P>0.05)。结论糖尿病合并脂肪肝患者较单纯糖尿病患者存在更严重的胰岛素抵抗、肥胖,同时存在更高水平的血脂、尿酸、转氨酶。
Objective To analyze the differences and characteristics of some clinical indexes between patients with diabetes mellitus and those with simple fatty liver. Methods A total of 153 patients with simple fatty liver without fatty liver were enrolled in the study. One hundred and forty-eight patients with fatty liver were enrolled as fatty liver group. The differences of some clinical indexes between the two groups were compared. Results The body mass index (BMI), ALT, AST, TC, LDL, TG ), Glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), C-peptide, uric acid (UA) were higher than those in non-steatohepatitis group, and their duration of diabetes was shorter than that in non-steatohepatitis group (P <0.05). There was no significant difference in gender, age, fasting blood glucose (FPG), Hb A1c and total bilirubin between the two groups (P> 0.05). Conclusion Patients with diabetes mellitus and fatty liver have more severe insulin resistance and obesity than those with simple diabetes mellitus, and have higher levels of blood lipids, uric acid and aminotransferase.