目的　分析 450例结核病人的治疗管理效果 ,总结经验 ,为搞好结防工作提供借鉴。方法　收集 1 999～2 0 0 0年结防科门诊收治的 450例结核病人 ,分析其治疗、管理的效果。结果　 450例结核病人完成疗程 2 71例 (60 .2 % ) ,痊愈 2 61例 ,好转 1 0例 ,完成疗程者治愈率达 96.3%。未完成疗程 1 79例 ,其中失访 75例 ,拒治 47例 ,转院治疗 32例 ,过诊过治 1 6例 ,误诊 4例 ,因其它疾病死亡 3例 ,因并发其它疾病中断治疗 2例。失访、拒治者中 ,外来人口 2 8例 (2 3.0 % ) ,本区人口 94例中农村患者 76例 (80 .9% ) ,≥ 60岁者 31例 (33.0 % )。结论　板式抗结核组合药服用方便 ,副作用少 ,疗效好。结核病的门诊督导全程管理治疗效果虽不及直接面视下短程化疗 (DOTS) ,但管理得当其效果可接近 DOTS。肺结核病控制的重点是痰菌阳性者 ,对于痰菌阴性者 ,应根据 X线胸片上病灶是否具有活动性来决定是否进行化疗 ,避免过诊过治。不能完成规定疗程的主要原因是对传染病防治知识和卫生法规宣传不够、随访不足及患者经济困难所致。外来人口流动性大 ,是结核病防治的难点 ,管理措施亟待解决 Objective To analyze the curative effect of 450 tuberculosis patients, summarize the experience and provide references for the prevention and control work. Methods A total of 450 tuberculosis patients admitted to the Department of Epidemiology and Outpatient Clinic from 1999 to 2000 were collected and their effects on treatment and management were analyzed. Results 450 cases of tuberculosis patients completed the course of 71 71 cases (60.2%), cured 2161 cases, improved 10 cases completed the cure rate of 96.3%. Incomplete treatment of 1 79 cases, of which 75 cases were lost, 47 cases refused treatment, transfer treatment of 32 cases, 16 cases of treatment, misdiagnosis in 4 cases, 3 cases of death due to other diseases, due to concurrent treatment of 2 cases of disrupted disease . Among the non-visiting and rejecting persons, 28 were migrants (3.03%), 76 were middle-rural residents (80.9%), and 31 (33.0%) were over 60. Conclusion Plate anti-tuberculosis combination medication convenient, less side effects, good effect. Tuberculosis outpatient supervision and management of the entire process, although not as effective as direct visualization of short-range chemotherapy (DOTS), but properly managed its effectiveness close to DOTS. The focus of tuberculosis control is sputum positive, for sputum negative, should be based on whether the lesions on the X-ray is active to decide whether to carry out chemotherapy, to avoid over-treatment. Can not complete the prescribed treatment is the main reason for the prevention and treatment of infectious diseases and health laws and regulations is not enough publicity, lack of follow-up and patients due to financial difficulties. The large mobility of migrants is a difficult point in the prevention and treatment of tuberculosis. Management measures need to be resolved urgently