目的　研究结核病控制三类不同干预措施对结核病病人疾病负担的影响。方法　采用WHO推荐的失能调整寿命年 (DALY)测算方法评价结核病病人的疾病负担。结果　例均初治TB病人 ,ITP地区为最轻 ,损失 0 31个DALY ;NTP地区居中 ,损失 0 42个DALY ;CTT地区为最重 ,损失 0 6 1个DALY ;例均复治TB病人 ,ITP为最轻 ,损失 0 6 2个DALY ;NTP居中 ,损失 0 5 9个DALY ;CTT为最重 ,损失0 91个DALY。从社会角度看 ,ITP地区每千人TB的DALY损失值年均为 16 42 ,NTP年均DALY损失值是 33 6 ,CTT年均DALY损失值是 37 36 ,NTP是ITP地区的 2 0 5倍 ,CTT是ITP的 2 2 8倍。结论　ITP在降低TB病人的疾病负担方面远胜于NTP与CTT ,不管从病人角度还是从社会角度 (社会发现率 ) ,其效果均较好 Objective To study the impact of three different types of interventions on tuberculosis control on the burden of disease in patients with tuberculosis. Methods The disease burden of patients with tuberculosis was assessed using the DALY method recommended by the WHO. Results In all patients with untreated TB, the l ITP area was the lightest with a loss of 0 31 DALY; the NTP area was centered with a loss of 0 42 DALY; the CTT area was the heaviest with a loss of 0 6 1 DALY; ITP was the lightest with a loss of 0.662 DALYs; median NTPs lost 0 59 DALYs; CTTs were heaviest with loss of 0 91 DALYs. From a social point of view, the average annual DALY loss per 1000 TB in ITP area is 16 42, the annual average DALY loss value of NTP is 33 6, the annual average DALY loss value of CTT is 37 36, and the NTP is 25 times higher than that in ITP area , CTT is 2 2 8 times of ITP. Conclusions ITP is far superior to NTP and CTT in reducing the disease burden of TB patients, and the effect is better both in terms of patients and from the social point of view (social discovery rate)