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目的评价黄芪联合卡络磺钠治疗肾综合征出血热少尿期的临床疗效。方法将110例出血热少尿期患者随机分成治疗组和对照组。对照组给予常规治疗,治疗组在对照组基础上采用黄芪联合卡络磺钠治疗。评价两组少尿期的恢复情况。结果治疗组与对照组比较,尿素氮(BUN)、血肌酐(Cr)、谷丙转氨酶(ALT)、谷草转氨酶(AST)均明显下降(P<0.05),血小板(Plt)水平明显升高(P<0.05);治疗组患者少尿期持续天数较对照组明显缩短(P<0.05)。结论黄芪联合卡络磺钠治疗肾综合征出血热较常规治疗效果好,少尿期明显缩短。
Objective To evaluate the clinical efficacy of Astragalus combined with sulfasalazine in the treatment of oliguria in patients with hemorrhagic fever with renal syndrome. Methods 110 patients with hemorrhagic fever and oliguria were randomly divided into treatment group and control group. Control group given conventional treatment, the treatment group on the basis of the control group with astragalus card combined with sodium sulfonamide treatment. Evaluation of two groups of oliguria recovery. Results Compared with the control group, the levels of BUN, Cr, ALT and AST were significantly decreased (P <0.05) and the levels of platelet (Plt) were significantly increased P <0.05). The duration of oliguria in treatment group was significantly shorter than that in control group (P <0.05). Conclusion Astragalus combined with carbadox sodium in treatment of hemorrhagic fever with renal syndrome than conventional treatment, oliguria was significantly shortened.