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目的探讨延迟结扎脐带对健康足月新生儿黄疸及红细胞增多症的影响。方法在吉林省妇幼保健院2014年6月-2015年1月分娩的足月新生儿为研究对象,随机分为观察组(492例)和对照组(例508)。观察组延迟脐带结扎2 min,对照组娩出后10 s内结扎脐带。比较新生儿黄疸发生率、每日经皮胆红素平均值、高胆红素血症的发生率、胆红素脑病发生率、红细胞增多症发生率等指标,分析延迟结扎脐带对新生儿黄疸及红细胞增多症的影响。结果两组新生儿黄疸发生率比较差异无统计学意义(P>0.05)。两组新生儿每日经皮胆红素平均值比较,观察组均高于对照组,但差异无统计学意义(P>0.05)。两组新生儿高胆红素血症发生率比较,差异无统计学意义(P>0.05)。两组新生儿均未发生胆红素脑病,差异无统计学意义(P>0.05)。两组新生儿红细胞压积均值及红细胞增多症发生率比较,观察组均高于对照组,差异具有统计学意义(P<0.05),但均无明显临床症状。结论延迟脐带结扎对新生儿黄疸无明显影响,不增加高胆红素血症发生率,可增加红细胞增多症发生率,但均无高粘滞血症临床症状,不需治疗。不会对新生儿健康产生不利影响。
Objective To investigate the effect of delayed ligation of umbilical cord on jaundice and polycythemia in healthy term neonates. Methods Full-term newborn infants delivered from June 2014 to January 2015 in Jilin Maternal and Child Health Hospital were randomly divided into observation group (492 cases) and control group (508 cases). The observation group delayed the cord ligation for 2 min, while the control group ligation of the cord within 10 s. The incidence of neonatal jaundice, the average percutaneous bilirubin, the incidence of hyperbilirubinemia, the incidence of bilirubin encephalopathy, the incidence of polycythemia and other indicators were compared to analyze delayed neonatal jaundice ligation And the impact of polycythemia. Results There was no significant difference in incidence of neonatal jaundice between the two groups (P> 0.05). The average daily transcutaneous bilirubin in two groups of newborns was higher than that in the control group, but the difference was not statistically significant (P> 0.05). The incidence of neonatal hyperbilirubinemia between the two groups, the difference was not statistically significant (P> 0.05). No bilirubin encephalopathy occurred in the two groups of newborns, the difference was not statistically significant (P> 0.05). The incidence of neonatal hematocrit and the incidence of polycythemia in both groups were significantly higher in the observation group than in the control group (P <0.05), but no obvious clinical symptoms were found. Conclusion Delayed umbilical cord ligation has no obvious effect on neonatal jaundice, does not increase the incidence of hyperbilirubinemia, can increase the incidence of polycythemia, but no clinical symptoms of hyperviscosity, without treatment. Will not adversely affect the health of newborns.