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目的:探讨我市药品不良反应(ADR)的特点及其规律。方法:对我市ADR监测中心接受的1 596例ADR报告,分别从ADR患者年龄及性别,引起ADR药品剂型、药品种类、给药途径,ADR临床表现、报告人、报告机构、关联性评价等进行分析,并统计分析严重ADR。结果:1 596例ADR报告中,新的ADR 108例,严重的ADR 27例;>60岁的患者占28.13%;引起ADR主要剂型、品种和给药途径分别是注射剂、抗菌药和静脉滴注;ADR临床表现以消化系统症状为主;医生和一级医院上报比例高。结论:不断加强ADR报告和监测,促进合理用药,保障用药安全。
Objective: To investigate the characteristics and laws of Adverse Drug Reaction (ADR) in our city. Methods: A total of 1 596 ADR reports accepted by ADR monitoring center in our city were collected from the age and sex of ADR patients, respectively, resulting in ADR drug formulations, drug categories, route of administration, ADR clinical manifestations, speakers, reporting agencies, relevance evaluation Analysis, and statistical analysis of severe ADR. Results: Of the 1 596 ADR cases, 108 cases were new ADR, 27 cases were severe ADR and 28.13% were patients aged> 60 years. The main forms, varieties and routes of administration of ADR were injection, antibacterial and intravenous drip The main clinical manifestations of ADR were digestive system symptoms. The doctors and first-class hospitals reported a high proportion of them. Conclusion: The ADR report and monitoring should be continuously strengthened to promote rational drug use and ensure the safety of medication.