论文部分内容阅读
目的:探讨麻醉后恢复室(PACU)内全身麻醉(全麻)患者低体温发生率及其影响因素。方法:收集2019年1月1日至12月31日北京大学人民医院PACU内的10 341例全麻患者资料。根据在PACU期间是否发生低体温,分为低体温组和非低体温组,采用倾向性评分匹配年龄和性别后,纳入低体温组336例,非低体温组336例。比较两组患者临床特征,采用多因素logistic回归模型分析PACU期间发生低体温的潜在影响因素。结果:2019年PACU内发生低体温339例,发生率3.3%。低体温组年龄(54.1±17.1)岁,男156例,女180例;非低体温组年龄(53.1±16.0)岁,男156例,女180例。两组患者年龄、性别、美国麻醉医师协会(ASA)分级、手术种类差异均无统计学意义(均n P>0.05)。与PACU期间非低体温组比较,低体温组患者体质指数(BMI)[(22.8±3.5)kg/mn 2比(24.7±4.2)kg/mn 2]、基线体温[(36.3±0.5)℃比(36.5±0.5)℃]较低,麻醉时间[(4.4±1.6)h比(3.2±1.5)h]、手术时间[(3.1±1.4)h比(2.1±1.3)h]较长,术中出血量、输血量、输液量较多(均n P<0.001)。多因素logistic回归分析结果显示,出血量大(L)(n OR=5.361,95%n CI:2.863~10.037,n P<0.001)、俯卧位手术(n OR=3.653,95%n CI:2.104~6.342,n P<0.001)、麻醉时间长(h)(n OR=1.421,95%n CI:1.227~1.646,n P<0.001)、全身麻醉+神经阻滞(n OR=1.708,95%n CI:1.026~2.843,n P=0.039)是PACU期间低体温的独立危险因素,而高BMI(n OR=0.849,95%n CI:0.801~0.900,n P0.05). Compared with the non-hypothermia group, the body mass index (BMI) [(22.8±3.5) kg/mn 2 vs (24.7±4.2) kg/mn 2] and baseline body temperature [(36.3±0.5)℃ vs (36.5±0.5)℃] were lower, and anesthesia time [(4.4±1.6) h vs (3.2±1.5) h] and operation time [(3.1±1.4) h vs (2.1±1.3) h] were longer in hypothermia group. The amount of intraoperative bleeding, blood transfusion and intravenous fluid was larger in hypothermia group (alln P<0.001). Multivariate logistic regression analysis showed that larger amount of blood loss (L) (n OR=5.361, 95%n CI: 2.863-10.037, n P<0.001), prone position operation (n OR=3.653, 95%n CI: 2.104-6.342, n P<0.001), longer anesthesia time (h) (n OR=1.421, 95%n CI: 1.227-1.646, n P<0.001), and general anesthesia combined with regional nerve block (n OR=1.708, 95%n CI: 1.026-2.843, n P=0.039) were independent risk factors of hypothermia in the PACU, and higher BMI (n OR=0.849, 95%n CI: 0.801-0.900, n P<0.001) was an independent protective factor.n Conclusions:The incidence of hypothermia in patients after general anesthesia in the PACU remains relatively high. Therefore, more attention should be paid to identify high-risk patients, and active preventive measures should be taken for the risk factors of hypothermia.