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本文对临床已诊断为急、慢性中毒性肝病160例患者,进行了23种实验室肝脏功能试验研究。急性患者的肝功能试验阳性发生率为PA70%(14/20),ADA55%(4/20)、ALT45%(9/20),CG40%(8/20),与其余19种试验比较有显著差异(P<0.01)。对慢性患者,以ILG100%(11/11),ITTT45 64。75%(90/139),Tf 52。59%(71/135),CG31.75%(40/126)最为敏感,与常用肝功能的ALT 比较有显著差异(P<0.01)。中毒性肝病的检验阳性频率,急性病例有30%患者同时出现6种以上试验阳性。慢性病例有35%患者可同时出现4种以上试验阳性。肝脏功能试验的灵敏度,在急性病例血清酶和PA 检查出现明显的阳性,而在慢性病例以廓清试验(ICG,ITTT45)及Tf 最为敏感。
In this paper, clinical laboratory diagnosis of acute and chronic toxic liver disease in 160 patients, conducted 23 kinds of laboratory liver function tests. The positive rates of liver function test in acute patients were PA70% (14/20), ADA55% (4/20), ALT45% (9/20) and CG40% (8/20), which were significantly different from the other 19 kinds of tests Difference (P <0.01). For chronic patients, ILG100% (11/11), ITTT45 64.75% (90/139), Tf 52.59% (71/135) and CG31.75% (40/126) Functional ALT was significantly different (P <0.01). Toxic liver disease test positive frequency, 30% of acute cases in patients with more than 6 positive tests. Chronic cases, 35% of patients can be more than 4 tests simultaneously positive. The sensitivity of the liver function test was significantly positive for serum enzyme and PA tests in acute cases and was most sensitive in the chronic cases with clearance tests (ICG, ITTT45) and Tf.