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研究了巴基斯坦产夜花仙人掌(Caclus grandiflora)等10种植物对心血管功能的抑制作用。将10种植物用乙醇浸提4周,真空干燥后用水和乙酸乙酯溶解制成各自提取物样品溶液。取离体兔心以Mc Ewens液灌流,提取物样品溶液按剂量以不同浓度加入并一起培养,记录心肌收缩力、心率、冠咏输出量三项指标。结果:夜花仙人掌(Cactus grandiflora)提取物在0.1μg剂量时可使心肌收缩力减弱55%,心率减少40%及冠脉输出量减
The inhibition of cardiovascular function by 10 species of plants such as Caclus grandiflora in Pakistan was studied. Ten plants were extracted with ethanol for 4 weeks, dried in vacuo and dissolved in water and ethyl acetate to prepare the respective extract sample solutions. The isolated rabbit hearts were perfused with Mc Ewens solution. The sample solution of the extract was added in different concentrations according to the dosage and incubated together. The three indexes of myocardial contractility, heart rate and crown output were recorded. Results: Cactus grandiflora extract reduced myocardial contractility by 55%, heart rate by 40%, and coronary output at 0.1 μg