目的:通过对肺栓塞误诊病例的临床特别分析,探讨肺栓塞的误诊原因,总结经验教训,减少肺栓塞的误诊率。方法:对20例肺栓塞误诊病例的临床资料进行回顾性分析。结果:20例初诊的肺栓塞患者全部误诊,误诊的时间6天～8个月,其中2例死亡。结论:PE是涉及多学科的疾病且患者缺乏典型临床表现及体征,应强化对PE的诊断意识,同时对高危人群采取预防措施。 OBJECTIVE: To investigate the causes of misdiagnosis of pulmonary embolism by summarizing the clinical special cases of misdiagnosis of pulmonary embolism, summarize the experience and lessons learned, and reduce the misdiagnosis rate of pulmonary embolism. Methods: The clinical data of 20 cases of misdiagnosis of pulmonary embolism were retrospectively analyzed. Results: Twenty patients with newly diagnosed pulmonary embolism were all misdiagnosed. The time of misdiagnosis was 6 days to 8 months, of which 2 patients died. Conclusion: PE is a multidisciplinary disease and the patients lack typical clinical manifestations and signs. It is necessary to strengthen the diagnosis awareness of PE and take precautionary measures for high-risk groups.